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89845-16-9

中文名稱 Gastrofensin AN 5 free base
英文名稱 Gastrofensin AN 5 free base
CAS 89845-16-9
分子式 C19H21ClN2O2
分子量 344.84
MOL 文件 89845-16-9.mol
89845-16-9 結(jié)構(gòu)式 89845-16-9 結(jié)構(gòu)式

基本信息

中文別名
化合物 T11367
英文別名
Gastrofensin AN 5 free base
Carbamic acid, [4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl]-, ethyl ester (9CI)

物理化學(xué)性質(zhì)

儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜

常見問題列表

生物活性
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體內(nèi)研究

Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs.

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