884-39-9
中文名稱
L-3-(3,4-二羥基苯基)-2-甲基丙氨酸鹽酸鹽
英文名稱
L-(-)-α-Methyldopa (hydrochloride)
CAS
884-39-9
分子式
C10H14ClNO4
分子量
247.68
MOL 文件
884-39-9.mol
884-39-9 結(jié)構(gòu)式
基本信息
中文別名
L-3-(3,4-二羥基苯基)-2-甲基丙氨酸鹽酸鹽 英文別名
L-(-)-&MK-351 hydrochloride
(-)-α-Methyldopa Hydrochloride
L-(-)-α-Methyldopa (hydrochloride)
L-(-)- Alpha -Methyldopa hydrochloride
3-hydroxy-a-methyl- L-Tyrosine hydrochloride
常見問題列表
生物活性
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) 是一種 α-腎上腺素能激動劑（對 α2-adrenergic receptors 有選擇性）。Methyldopa hydrochloride 是一種前藥，在中樞神經(jīng)系統(tǒng)中被代謝 (α-Methylepinephrine)。體內(nèi)研究
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
| Animal Model: | 60-day-old male rats |
| Dosage: | 200 mg/kg |
| Administration: | I.p. |
| Result: | Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration. |