87697-99-2
中文名稱(chēng)
化合物 T24260
英文名稱(chēng)
kelletinin I
CAS
87697-99-2
分子式
C32H26O12
分子量
602.542
MOL 文件
87697-99-2.mol
87697-99-2 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
The inhibitory effect of esters of p-hydroxybenzoic acid (kelletinins I and A), extracted from the marine gastropod Buccinulum corneum, have been tested on eukaryotic and prokaryotic enzymes of DNA metabolism such as DNA polymerases alpha and beta, DNA polymerase I, Exo III, pancreatic DNAse I, micrococcal DNAse and E. coli RNA polymerase. Kelletinin I and kelletinin A inhibit preferentially DNA polymerase alpha. The inhibitory effect of kelletinin I involves the hydroxyl group of p-hydroxybenzoic acid