863239-61-6
中文名稱
奧貝膽酸雜質(zhì)9
英文名稱
Tauro Obeticholic acid
CAS
863239-61-6
分子式
C28H49NO6S
分子量
527.76
MOL 文件
863239-61-6.mol
更新日期
2024/04/28 11:58:04
863239-61-6 結(jié)構(gòu)式
基本信息
中文別名
?；?膽固醇?；酋W貝膽酸
英文別名
Tauro Obeticholic acidObeticholic Acid Impurity 56
Tauro-Obeticholic Acid DISCONTINUED. Please see T009025.
Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
Obeticholic Acid Impurity 4/Tauro-Obeticholic Acid/2-((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-Ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid
所屬類(lèi)別
有機(jī)原料：羧酸類(lèi)化合物及衍生物物理化學(xué)性質(zhì)
密度1.177±0.06 g/cm3(Predicted)
儲(chǔ)存條件Store at -20°C, protect from light, stored under nitrogen
溶解度DMSO: soluble; Methanol: soluble; Water: soluble
酸度系數(shù)(pKa)1.42±0.50(Predicted)
形態(tài)固體
顏色White to yellow
穩(wěn)定性吸濕性
奧貝膽酸雜質(zhì)9價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | HY-135399 | 奧貝膽酸雜質(zhì)9 Tauro-Obeticholic acid | 863239-61-6 | 1mg | 5500元 |
常見(jiàn)問(wèn)題列表
生物活性
Tauro-Obeticholic acid 是牛磺酸的活性代謝物。Obeticholic Acid 是一種口服生物可利用的法尼樣X(jué)受體 (FXR) 激動(dòng)劑。體外研究
Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.