850559-51-2
850559-51-2 結(jié)構(gòu)式
常見問題列表
生物活性
BMVC2 (o-BMVC) 是 BMVC 的雙取代咔唑衍生物,是一種 G 四聯(lián)體 (G4) 穩(wěn)定劑。靶點(diǎn)
G-quadruplex
體外研究
BMVC2 by monitoring the disappearance of the 291 nm CD signals of d[AG 3 (T 2 AG 3 ) 3 ] (HT22) after adding Cu2+ is screened, a longer unfolding time would dictate a better G4 stabilizer. The unfolding curve of HT22 in the presence of BMVC2 can be fitted by using two time constants of 133.7 s (29%) and 2816 s (71%), which are similar to the unfolding parameters of BMVC.