78299-79-3
中文名稱
2,3-dihydro-7-methyl-9-phenyl-1H-pyrazolo(1,2-a)indazolium
英文名稱
2,3-dihydro-7-methyl-9-phenyl-1H-pyrazolo(1,2-a)indazolium
CAS
78299-79-3
MOL 文件
78299-79-3.mol

常見問題列表
生物活性
FKK 是一種吲唑衍生物,也是一種新型支氣管擴張劑。體內(nèi)研究
FKK is an indazole derivative and also a novel bronchodilator. FKK (0.1 to 3.0 mg/kg, i.v.) slightly increases respiratory frequency, left ventricular (LV) dp/dt max and myocardial contractile force. A slight increase followed by a decrease is observed in systemic blood pressure and LV systolic pressure. FKK causes direct vasodilation in the coronary, mesenteric and femoral vasculatures, but has no effect on the renal vasculature. It is particularly pertinent that FKK (30 mg/kg, i.d., enough to cause marked bronchodilation), unlike aminophylline (30 mg/kg, i.d.), does not significantly influence the cardiovascular system.