76461-17-1
中文名稱
SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY- CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(DISULFIDE BRIDGE: CYS14-CYS25)
CAS
76461-17-1
分子式
C127H191N37O34S3
分子量
2876.33
MOL 文件
76461-17-1.mol
更新日期
2024/10/20 11:27:47
76461-17-1 結(jié)構(gòu)式
基本信息
英文別名
SOMATOSTATIN-25SNPAMAPRERKAGCKNFFWKTFTSC
Somatostatin-25 (sheep) (9CI)
SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS
H-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH
SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY- CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(DISULFIDE BRIDGE: CYS14-CYS25)
(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-37-[[2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-4-amino-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-oxobutanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]-4-carboxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]propanoyl]amino]acetyl]amino]-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1~{
常見問題列表
生物活性
Somatostatin-25 是一種內(nèi)源性神經(jīng)肽激素，能夠抑制生長激素的分泌。體外研究
Somatostatin-25 (0.1 pM-1 nM) significantly inhibits secretion of growth hormone in the in vitro system, and is 3-14 times more effective than the tetradecapeptide. Somatostatin-25 (0.1 nM-1pM) also inhibits secretion of growth hormone induced by the addition of prostaglandin 2 (PGE2). However, Somatostatin-25 shows no effect on the secretion of prolactin.