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72122-62-4

中文名稱 Β-酪啡肽-7
英文名稱 BETA-CASOMORPHIN (BOVINE)
CAS 72122-62-4
分子式 C41H55N7O9
分子量 789.92
MOL 文件 72122-62-4.mol
更新日期 2024/12/16 11:45:51
72122-62-4 結(jié)構(gòu)式 72122-62-4 結(jié)構(gòu)式

基本信息

中文別名
Β-酪啡肽-7
嬰兒猝死綜合征/酪啡肽Β/-CASOMORPHIN抗體
英文別名
YPFPGPI
β-Casomorphin-7
BETA CASOMORPHIN
BETA-CASOMORPHIN-7
β-Casomorphin 7【ox】
β-Casomorphin-7【ox】
β-Casomorphin, bovine
β-Casomorphin(cattle)
b-Casomorphin (bovine)
BETA-CASOMORPHIN (BOVINE)

物理化學(xué)性質(zhì)

儲存條件-15°C
溶解度Soluble in DMSO
形態(tài)Solid
顏色White to off-white
Β-酪啡肽-7價(jià)格(試劑級)
報(bào)價(jià)日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價(jià)格
2024/11/08HY-P0179Β-酪啡肽-7
β-Casomorphin, bovine
72122-62-45mg800元
2024/11/08HY-P0179Β-酪啡肽-7
β-Casomorphin, bovine
72122-62-410mg1400元
2024/11/08HY-P0179Β-酪啡肽-7
β-Casomorphin, bovine
72122-62-425 mg2900元

常見問題列表

生物活性
β-casomorphin, bovine (β-Casomorphin-7 (bovine) ) 是阿片 (opioid) 活性的多肽,與阿片受體結(jié)合的 IC50 值為 14 μM。
靶點(diǎn)

IC50: 14 μM (Opioid receptor)

體外研究

β-Casomorphin, bovine (0.1 μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment.
β-Casomorphin, bovine (0.1 μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels.
β-Casomorphin, bovine do not modify the expression of rMuc1, rMuc4, and rMuc5AC.
β-Casomorphin, bovine (0.1 μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).

體內(nèi)研究

β-Casomorphin, bovine (7.5×10 ?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats.
β-Casomorphin, bovine (7.5×10 ?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats.
β-Casomorphin, bovine (7.5×10 ?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats.
β-Casomorphin, bovine (7.5×10 ?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.

Animal Model: Male Sprague-Dawley (SD) rats (200 g±10 g)
Dosage: 7.5×10 ?6 mol/day/kg
Administration: Oral gavage; for 30 days
Result: Increased plasma insulin and decreased plasma glucagon of diabetic rats.
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