71902-47-1
中文名稱
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
英文名稱
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
CAS
71902-47-1
分子式
C20H30O5
分子量
350.45
MOL 文件
71902-47-1.mol
71902-47-1 結構式
基本信息
中文別名
9Α,15S-二羥基-11-氧代-前列腺素5Z,13E,17Z-三烯-1-油酸 英文別名
PGD3PROSTAGLANDIN D3
Prostaglandin D3
ANOICLBSJIMQTA-WXGBOJPQSA-N
Prostaglandin D3 Exclusive
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
(5Z,13E,15S,17Z)-9α,15-Dihydroxy-11-oxoprosta-5,13,17-trien-1-oic acid
(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-3-oxocyclopentyl]hept-5-enoic acid
物理化學性質
儲存條件-20°C儲存
溶解度DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2)
應用領域
用途一
Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway. It is equipotent to PGD2 in decreasing systemic blood pressure in rats and in decreasing intraocular pressure in rabbits. However, it is 3-5 times more potent than PGD2 in the inhibition of ADP-induced human platelet aggregation.[Cayman Chemical]