711085-63-1
中文名稱
PNU-282987
英文名稱
Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
CAS
711085-63-1
分子式
C14H17ClN2O
分子量
264.75
MOL 文件
711085-63-1.mol
更新日期
2024/11/05 13:11:14
711085-63-1 結構式
基本信息
中文別名
N-(3R)-1-氮雜雙環(huán)[2.2.2]辛-3-基-4-氯-苯甲酰胺 英文別名
PNU 282987 free base(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide
4-chloro-N-[(3R)-quinuclidin-3-yl]benzamide
Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide
應用領域
用途一
PNU-282987 is a highly selective α7 nicotinic acetylcholine receptor agonist (1,2). PNU-282,987 has been utilized to generate retinal neurons in the absence of retinal injury or exogenous growth factors in rat (1). PNU-282,987 has the potential to reverse vision loss due to neurodegenerative disease or aging.