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709641-79-2

中文名稱 (1R,3R,4R,7S)-1-((雙(4-甲氧基苯基)苯基)甲氧基)甲基)-3-(2-(((二甲基氨基)亞甲基)氨基)-6-氧代-3H-嘌呤-9(6H)-基)-2,5-二氧雜雙環(huán)[2.2.1]庚烷-7-基 (2-氰乙基)二異丙基亞磷酰胺
英文名稱 (E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
CAS 709641-79-2
分子式 C44H53N8O8P
分子量 852.91
MOL 文件 709641-79-2.mol
709641-79-2 結(jié)構(gòu)式 709641-79-2 結(jié)構(gòu)式

基本信息

中文別名
N2-DMF-2'-O-4'-C-LOCKED-GR-CE-亞磷酰胺
(1R,3R,4R,7S)-1-((雙(4-甲氧基苯基)苯基)甲氧基)甲基)-3-(2-(((二甲基氨基)亞甲基)氨基)-6-氧代-3H-嘌呤-9(6H)-基)-2,5-二氧雜雙環(huán)[2.2.1]庚烷-7-基 (2-氰乙基)二異丙基亞磷酰胺
(1R,3R,4R,7S)-1-((雙(4-甲氧基苯基)(苯基)甲氧基)甲基)-3-(2-(((二甲氨基)亞甲基)氨基)-6-氧代-3,6 -二氫-9H-嘌呤-9-基)-2,5-二氧雜二環(huán)[2.2.1]庚-7-基(2-氰乙基)二異丙基亞磷酰胺
英文別名
LNA-N-dmf Guanosine? Amidite
LNA-guanosine 3'-CE phosphoramidite
LNA-guanosine 3'-CE phosphoramidite
2'-O-4'-C-Locked-rG(dmf) Phosphoramidite
DMTr-2'-O-4'-C-Locked-rG(dmf)-3'-CE-Phosphoramidite
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-(((dimethylamino)methylene)amino)-6-oxo-3H-purin-9(6H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-(((dimethylamino)methylene)amino)-6-oxo-3,6-dihydro-9H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
Methanimidamide, N'-[9-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethyl- (9CI)
(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide

物理化學(xué)性質(zhì)

沸點(diǎn)894.1±75.0 °C(Predicted)
酸度系數(shù)(pKa)3.70±0.20(Predicted)
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