68483-33-0
中文名稱
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
英文名稱
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
CAS
68483-33-0
分子式
C27H23ClN2O5
分子量
490.93
MOL 文件
68483-33-0.mol
68483-33-0 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10355化合物APYRAMIDE
英文別名
apyramide4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester
物理化學(xué)性質(zhì)
熔點(diǎn)145-150 °C(Solv: benzene (71-43-2); methanol (67-56-1))
沸點(diǎn)671.1±55.0 °C(Predicted)
密度1.29±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)14.20±0.70(Predicted)
形態(tài)Solid
顏色White to off-white
4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-U00046 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide | 68483-33-0 | 5mg | 2000元 |
| 2024/11/08 | HY-U00046 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide | 68483-33-0 | 10mg | 3400元 |
| 2024/11/08 | HY-U00046 | 4-(acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Apyramide | 68483-33-0 | 20mg | 6000元 |
常見問題列表
生物活性
Apyramide 是一種抗炎試劑 (NSAID)，是吲哚美辛 (HY-14397) 的前藥。Indomethacin 是一種強(qiáng)效的、血腦通透的、非選擇性的 COX1 和 COX2 抑制劑。體內(nèi)研究
Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities.