62030-88-0
中文名稱(chēng)
Duoperone
英文名稱(chēng)
Duoperone
CAS
62030-88-0
分子式
C28H26F4N2OS
分子量
514.58
MOL 文件
62030-88-0.mol
62030-88-0 結(jié)構(gòu)式
基本信息
中文別名
化合物 T11121 英文別名
Methanone, (4-fluorophenyl)[1-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinyl]-物理化學(xué)性質(zhì)
沸點(diǎn)613.5±55.0 °C(Predicted)
密度1.289±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)8.12±0.10(Predicted)
常見(jiàn)問(wèn)題列表
生物活性
Duoperone 是一種安定劑，同時(shí)在動(dòng)物模型中，也是一種止吐劑。體內(nèi)研究
Duoperone blocks d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval is between one hour and seven days. ABR-6646 produces catalepsy in rats. The onset of this effect is delayed and the duration is prolonged when compared with that of chlorpromazine. Apomorphine-induced pivoting in mice with unilateral lesions of the caudate nucleus is suppressed by ARR-6646.