59979-01-0
中文名稱
高硫青霉素I
英文名稱
44-O-DeMethylthiocillin II
CAS
59979-01-0
分子式
C48H49N13O10S6
分子量
1160.37
MOL 文件
59979-01-0.mol
59979-01-0 結(jié)構(gòu)式
基本信息
中文別名
高硫青霉素I 英文別名
Thiocillin I44-O-DeMethylthiocillin II
[2,4'-Bithiazole]-4-carboxamide, 2'-[(11S,14Z,21S,28S)-14-ethylidene-9,10,11,12,13,14,20,21,27,28-decahydro-11,28-bis[(1R)-1-hydroxyethyl]-21-(1-hydroxy-1-methylethyl)-9,12,19,26-tetraoxo-19H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriac...
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
形態(tài)固體
常見問題列表
生物活性
Thiocillin I 是一種硫肽抗生素，對(duì)革蘭氏陽性細(xì)菌菌株具有體外抗菌活性。Thiocillin I 對(duì)金黃色葡萄球菌 1974149 菌株，糞腸球菌 1674621 菌株，枯草芽孢桿菌 ATCC 6633 菌株和化膿鏈球菌 1744264 菌株的 MIC 值分別為 2 μg/ mL，0.5 μg/ mL，4 μg/ mL 和 0.5 μg/ mL。靶點(diǎn)
Bacterial
體外研究
Thiocillin I (2 μM; 24 hours; U-2OS C3 osteosarcoma cells) is not proteasome inhibitor, and does not stabilize expression of multiple cellular proteins and suppresses FoxM1 expression in U-2OS C3 osteosarcoma cells.