536759-91-8
中文名稱(chēng)
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯
英文名稱(chēng)
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS
536759-91-8
分子式
C22H20N4O6
分子量
436.42
MOL 文件
536759-91-8.mol
更新日期
2025/02/24 09:54:38
536759-91-8 結(jié)構(gòu)式
基本信息
中文別名
阿哌沙班雜質(zhì) G阿哌沙班雜質(zhì)80S
進(jìn)口資料代碼-BMS-778960-01
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸
1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-4,5,6,7-四氫-1H-吡唑啉[3,4-C]吡啶-3-羧酸乙酯
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯(阿哌沙班中間體)
4,5,6,7-四氫-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯(阿哌沙班中間體) 10G
乙基 1H-吡唑并[3,4-C]吡啶-3 - 羧酸的酸,4,5,6,7 - 四氫-1 - (4 - 甲氧基苯基)-6 - (4 - 硝基苯基)-7 - 氧代乙基酯
英文別名
EOS-61014Apixaban iMpurityG
-6-(4-nitrophenyl)
Apixaban Impurity 80
Apixaban impurity BMS-589154
-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
所屬類(lèi)別
分析化學(xué)：對(duì)照品物理化學(xué)性質(zhì)
熔點(diǎn)190-192°C
沸點(diǎn)658.7±55.0 °C(Predicted)
密度1.40
蒸氣壓0Pa at 25℃
儲(chǔ)存條件Sealed in dry,Room Temperature
溶解度氯仿（微溶）、乙酸乙酯（微溶）
酸度系數(shù)(pKa)-3.80±0.20(Predicted)
形態(tài)固體
顏色淺棕色至淺橙色
InChIInChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3
InChIKeyRQNAOIQEGPVYTC-UHFFFAOYSA-N
SMILESC1(=O)N(C2=CC=C([N+]([O-])=O)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2
LogP3.59 at 23℃ and pH6.57
