487-79-6
中文名稱
紅藻氨酸, **
英文名稱
KAINIC ACID
CAS
487-79-6
分子式
C10H15NO4
分子量
213.23
MOL 文件
487-79-6.mol
更新日期
2024/11/07 22:56:16
487-79-6 結(jié)構(gòu)式
基本信息
中文別名
卡英酸鷓鴣菜酸
紅藻胺酸
海人草酸
紅藻氨酸, **
ALPHA-紅藻氨酸
(2S,3S,4S)-3-(羧基甲基)-4-(丙-1-烯-2-基)吡咯烷-2-羧酸
英文別名
KAINATE(-)-α-Kainic Acid
Kainic
C12819
digenin
helminal
(3a&alpha
Kainicaci
,4-beta))-
KAINIC ACID
所屬類別
有機(jī)原料：羧酸類化合物及衍生物物理化學(xué)性質(zhì)
熔點(diǎn)253-254 C
比旋光度D24 -14.8° (c = 1.01)
沸點(diǎn)353.22°C (rough estimate)
密度1.2177 (rough estimate)
折射率1.4368 (estimate)
儲(chǔ)存條件2-8°C
儲(chǔ)存條件Keep in dark place,Sealed in dry,2-8°C
溶解度H2O: soluble
溶解度可溶于水中
酸度系數(shù)(pKa)2.03±0.60(Predicted)
形態(tài)白色至類白色固體
顏色白色
水溶解性Soluble to 25 mM in water
穩(wěn)定性自購(gòu)買(mǎi)之日起 1 年內(nèi)保持穩(wěn)定。蒸餾水溶液可在 -20° 下保存長(zhǎng)達(dá) 3 個(gè)月。
InChIInChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChIKeyVLSMHEGGTFMBBZ-OOZYFLPDSA-N
SMILESN1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302-H312-H332
危險(xiǎn)品標(biāo)志Xn
危險(xiǎn)類別碼20/21/22
安全說(shuō)明22-24/25-36
WGK Germany3
WGK Germany3
常見(jiàn)問(wèn)題列表
生物活性
Kainic acid 是 CNS 中興奮性氨基酸受體亞型的有效激動(dòng)劑。體內(nèi)研究
Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus.