473930-22-2
473930-22-2 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
熔點(diǎn)248.5-252 °C(Solv: methanol (67-56-1))
密度1.322±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)10.30±0.20(Predicted)
形態(tài)Solid
顏色Off-white to light yellow
應(yīng)用領(lǐng)域
用途一
SM-276001 is a selective and potent TLR7 agonist. SM-276001 is can induce antitumor immune responses when dosed either intratracheally or orally. Oral administration of SM-276001 leads to the induction of IFNα, TNFα and IL-12p40 and a reduction in tumor burden in the Balb/c syngeneic Renca and CT26 models.