432029-12-4
中文名稱
化合物 T27121
英文名稱
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl
CAS
432029-12-4
分子式
C33H38N4O10
分子量
650.69
MOL 文件
432029-12-4.mol
432029-12-4 結(jié)構(gòu)式
基本信息
中文別名
化合物 T27121 英文別名
YM222714YM-222714
YM 222714
Darexaban glucuronide
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl
應(yīng)用領(lǐng)域
用途一
Darexaban glucuronide, also known as YM-222714, is the major component in plasma after oral administration of darexaban to humans and is the pharmacologically active metabolite. Darexaban (YM150) is a direct inhibitor of factor Xa. It is an experimental drug that acts as an anticoagulant and antithrombotic to prevent venous thromboembolism after a major orthopaedic surgery, stroke in patients with atrial fibrillation and possibly ischemic events in acute coronary syndrome. It is used in form of the maleate. The development of darexaban was discontinued in September 2011.