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39740-30-2

中文名稱 L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
CAS 39740-30-2
分子式 C11H16ClNO4
分子量 261.702
MOL 文件 39740-30-2.mol
39740-30-2 結(jié)構(gòu)式 39740-30-2 結(jié)構(gòu)式

基本信息

中文別名
左旋多巴乙酯鹽酸鹽
L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
英文別名
Etilevodopa hydrochloride
O-Ethyl-DOPA Hydrochloride
L-DOPA Ethyl Ester Hydrochloride
Levodopa Ethyl Ester Hydrochloride
3-Hydroxy-L-tyrosine Ethyl Ester Hydrochloride
3-hydroxy- L-Tyrosine ethyl ester, hydrochloride (1:1)
3,4-Dihydroxy-L-phenylalanine Ethyl Ester Hydrochloride

物理化學(xué)性質(zhì)

熔點(diǎn)51-54°C
儲(chǔ)存條件Hygroscopic, Refrigerator, Under Inert Atmosphere

應(yīng)用領(lǐng)域

用途1
An active ingredient in preparations for the treatment of Parkinson鈥檚 disease.
L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-116016AL-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
Etilevodopa hydrochloride
39740-30-25mg350元
2024/11/08HY-116016AL-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
Etilevodopa hydrochloride
39740-30-210mM * 1mLin Water390元
2024/11/08HY-116016AL-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
Etilevodopa hydrochloride
39740-30-210mg600元

常見問(wèn)題列表

生物活性
Etilevodopa hydrochloride (L-Dopa ethyl ester hydrochloride) 是 Levodopa 的前藥,在胃腸道中被非特異性酯酶快速水解為 Levodopa 和乙醇。Etilevodopa 用于帕金森病 (PD)的相關(guān)研究。Levodopa 是多巴胺的直接前體,有助于中樞神經(jīng)系統(tǒng)的滲透和傳遞多巴胺。
體外研究

Etilevodopa (L-Dopa ethyl ester) hydrochloride passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa.
Compared with standard Levodopa, Etilevodopa hydrochloride has greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration.

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