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2470-73-7

中文名稱 地西拉嗪
英文名稱 2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol
CAS 2470-73-7
分子式 C24H33N3O2S
分子量 427.6
MOL 文件 2470-73-7.mol
2470-73-7 結(jié)構(gòu)式 2470-73-7 結(jié)構(gòu)式

基本信息

中文別名
地西拉嗪
英文別名
Esucos
UCB-3412
Dixyrazine
2-[2-[4-(2-methyl-3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethoxy]ethanol
2-[2-[4-(2-methyl-3-phenothiazin-10-yl-propyl)piperazin-1-yl]ethoxy]ethanol
2-[2-[4-[2-Methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]ethanol
2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol
Ethanol,2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethoxy]-
所屬類別
生物化工:抑制劑

物理化學(xué)性質(zhì)

熔點(diǎn)192 °C
沸點(diǎn)590.0±50.0 °C(Predicted)
密度1.0745 (rough estimate)
折射率1.6740 (estimate)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)pKa1: 7.8; pKa2: 3.65(at 25℃)
形態(tài)Solid
顏色White to off-white
地西拉嗪價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-U00153地西拉嗪
Dixyrazine
2470-73-71mg2400元
2024/11/08HY-U00153地西拉嗪
Dixyrazine
2470-73-710 mM * 1 mLin DMSO4704元
2024/11/08HY-U00153地西拉嗪
Dixyrazine
2470-73-75mg5000元

常見問題列表

生物活性
Dixyrazine 是 Phenothiazine 衍生物,可預(yù)防注射硫酸魚精蛋白引起的腦水腫。
體內(nèi)研究

Pretreatment with Dixyrazine 10 mg/kg completely prevents the brain oedema and significantly reduces the albumin increase in cerebrospinal fluid (CSF). The phenothiazine Dixyrazine (5 mg/kg i.v.) has minimal, transient hypotensive effects but significantly reduces the leakage of 126 I labelled serum albumin in conscious rats subjected to acute hypertension provoked by i.v. Adrenaline or Bicuculline. The diameters of pial arteries and veins are continuously measured with a multichannel videoangiometer through a closed cranial window in anesthetized rats before and after i.v. injection of Dixyrazine (5 mg/kg). Dixyrazine, 5 mg /kg, induces a slight transitory decrease in blood pressure (10-20 mm Hg). Maximum MAP is slightly but not significantly lower in Dixyrazine-treated rats.

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