2410279-82-0
中文名稱
Taurodeoxycholic Acid-[d4] Sodium Salt
英文名稱
Taurodeoxycholic Acid-[d4] Sodium Salt
CAS
2410279-82-0
分子式
C26H46NNaO6S
分子量
523.7
MOL 文件
2410279-82-0.mol
更新日期
2025/02/05 10:07:35
2410279-82-0 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C
溶解度DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 3 mg/ml
形態(tài)結(jié)晶固體
應(yīng)用領(lǐng)域
用途一
Taurodeoxycholic acid-d4 is intended for use as an internal standard for the quantification of taurodeoxycholic acid by GC- or LC-MS. Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally. Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.