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2247491-97-8

中文名稱 NPB
英文名稱 NPB
CAS 2247491-97-8
分子式 C29H31Cl2N3O2
分子量 524.48
MOL 文件 2247491-97-8.mol
2247491-97-8 結(jié)構(gòu)式 2247491-97-8 結(jié)構(gòu)式

物理化學(xué)性質(zhì)

沸點(diǎn)688.0±55.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
酸度系數(shù)(pKa)9.87±0.35(Predicted)
形態(tài)Solid
顏色White to off-white

應(yīng)用領(lǐng)域

用途一
IUN91978, also known as NPB, is a specific inhibitor of the phosphorylation of human BCL-2-associated death promoter (hBAD) specifically on Ser99, thereby exerting its effect independently of AKT and other kinase activities despite the demonstration of AKT-mediated BAD-Ser99 phosphorylation. NPB was reported by Pandey V et al in PNAS. 2018, 115(44):E10505-E10514. This product has no formal name at the moment.

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