2243944-92-3
中文名稱
Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy-
英文名稱
Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy-
CAS
2243944-92-3
分子式
C18H16Cl2N4O2
分子量
391.25
MOL 文件
2243944-92-3.mol
更新日期
2024/12/23 10:32:37
2243944-92-3 結(jié)構(gòu)式
基本信息
中文別名
化合物UUN44923 英文別名
FTO-IN-1UUN44923
Dac51，UUN-44923
Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy-
物理化學(xué)性質(zhì)
密度1.448±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: 100 mg/mL (197.91 mM);Water: Insoluble;Ethanol: Insoluble
酸度系數(shù)(pKa)8.72±0.40(Predicted)
應(yīng)用領(lǐng)域
用途一
UUN44923 is a FTO inhibitor. UUN44923 may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS)?, type 2 diabetes (T2D)?, Alzheimer's diseases, breast cancers, small-?cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like. UUN44923 was reported in WO 2018157843. This product has no formal name at the moment.