2243709-60-4
2243709-60-4 結構式
基本信息
中文別名
化合物 T11131 英文別名
DW148006-Isoquinolinecarboxamide, N-[3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-2-[4-(dimethylamino)benzoyl]-1,2,3,4-tetrahydro-
物理化學性質
沸點754.9±60.0 °C(Predicted)
密度1.229±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)13.91±0.20(Predicted)
形態(tài)Solid
顏色White to off-white
應用領域
用途一
DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor. It reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. DW14800 has anti-cancer activity.