2234271-86-2
2234271-86-2 結(jié)構(gòu)式
基本信息
中文別名
化合物JI130 英文別名
JI-130)JI130 (JI 130
2-Propenamide, 3-(7-methoxy-1H-indol-3-yl)-N-[2-[2-(2-propen-1-yloxy)phenyl]ethyl]-, (2E)-
應用領(lǐng)域
用途一
JI130 is an inhibitor of the cancer-associated transcription factor Hes1 via the PHB2 chaperone. JI130 stabilizes PHB2's interaction with Hes1 outside the nucleus, inducing G2/M cell cycle arrest.