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22204-24-6

中文名稱 雙羥萘酸噻嘧啶
英文名稱 Pyrantel pamoate
CAS 22204-24-6
分子式 C34H30N2O6S
分子量 594.68
MOL 文件 22204-24-6.mol
更新日期 2024/12/23 10:31:53
22204-24-6 結(jié)構(gòu)式 22204-24-6 結(jié)構(gòu)式

基本信息

中文別名
(E)-1-甲基-2-[2-(2-噻吩基)乙烯基]-1,4,5,6-四氫嘧啶 4,4'-亞甲基-雙(3-羥基2-奈酸)鹽
雙羥萘酸噻嘧啶
雙羥乃酸噻嘧啶
恩波酸噻嘧啶
抗蟲靈
雙羥萘酸喹嘧啶
雙羥萘酸噻嘧啶(噻嘧啶)
英文別名
1-METHYL-2-(2-[2-THIENYL]ETHENYL)-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID)
PYRANTEL PAMOATE
PYRANTEL PAMOATE SALT
PYRANTEL PAMOTE
2-naphthoicacid,4,4’-methylenebis(3-hydroxy-,compd.with(e)-1,4,5,6-tetrahy
antiminth
dro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine(1:1)
embovin
pyrantelembonate
1,4,5,6-tetrahydro-1-methyl-2-((E)-2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate)
4,4'-methylenebis(3-hydroxy-2-naphthoic acid) compounded with (E)-1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine (1:1)
cobantril
combantrin
cp-10423-16
Dog Wormer
helmex
lombriareu
pirantel pamoate
pyrantel pamoate sigmaultra
trilombrin
所屬類別
原料藥:驅(qū)腸蟲藥

物理化學(xué)性質(zhì)

外觀性狀黃色至褐色晶體粉末
熔點(diǎn)266-267°C
儲(chǔ)存條件0-6°C
溶解度Pratically insoluble in water, soluble in dimethyl sulfoxide, pratically insoluble in methanol.
形態(tài)powder
顏色yellow
水溶解性<0.1 g/100 mL at 19 ºC
BRN9034755
BCS Class4
InChIKeyAQXXZDYPVDOQEE-MXDQRGINSA-N
SMILESC(C1=C(C(C(=O)O)=CC2=CC=CC=C12)O)C1=C(C(C(=O)O)=CC2=CC=CC=C12)O.C(/C1=NCCCN1C)=C\C1SC=CC=1

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
WGK Germany3
RTECS號(hào)QL2287000
海關(guān)編碼2934990002
雙羥萘酸噻嘧啶價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/0846189雙羥萘酸噻嘧啶, 98%
Pyrantel pamoate, 98%
22204-24-65g551元
2024/11/0846189雙羥萘酸噻嘧啶, 98%
Pyrantel pamoate, 98%
22204-24-625g1604元
2024/11/0846189雙羥萘酸噻嘧啶, 98%
Pyrantel pamoate, 98%
22204-24-6100g5505元

常見問題列表

生物活性
Pyrantel pamoate (Pyrantel Embonate)是一種廣譜驅(qū)蟲劑,用于治療一些寄生蟲感染。
體外研究

Pyrantel induces Ascaris suum muscle contraction, with a pEC 50 of 7.24.
Pyrantel produces spastic paralysis of the nematode by selectively gating acetylcholine receptor ion-channels on nerve and muscle.
Pyrantel (72 h) inhibits the survival of Ancylostoma ceylanicum , Necator americanus and Trichuris muris on the third-stage larvae (IC 50 s=90.9, 2.0, and 95.5 μg/mL, respectively) and adult worms (IC 50 s=>100, 7.6, and 34.1 μg/mL, respectively).

體內(nèi)研究

Pyrantel (10 mg/kg; a single p.o.) reduces the worms in A. ceylanicum -infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.

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