21738-42-1
21738-42-1 結(jié)構(gòu)式
基本信息
中文別名
羥氨喹奧沙尼喹
硝羥四氫喹啉胺
英文別名
Vansilmansil
uk4261
uk4271
NSC 352888
oxamniquine
UK 4271/Vansil
oxamniquinum(inn-latin)
oxamniquina(inn-spanish)
OXAMNIQUINE(200MG)DISCONTINUED
物理化學(xué)性質(zhì)
熔點(diǎn)147-149°
沸點(diǎn)422.1°C (rough estimate)
密度1.1119 (rough estimate)
折射率1.5700 (estimate)
酸度系數(shù)(pKa)pKa 3.28 ± 0.07;9.53(H2O,t =25) (Uncertain)
顏色淡橙色粉末
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302-H413
防范說(shuō)明P264-P270-P301+P312-P330-P501
毒性LD50 in mice, rabbits (mg/kg): >2000, >1000 i.m., 1300, 800 orally (Foster)
常見(jiàn)問(wèn)題列表
生物活性
Oxamniquine 是一種有效的抗血吸蟲(chóng)病試劑。靶點(diǎn)
Parasite
體外研究
Oxamniquine is a potent agent for the treatment of schistosomiasis.
體內(nèi)研究
Oxamniquine (500 mg/kg) alone or Oxamniquine (250 mg/kg) in combination with praziquantel reduces the mortality of infected snails compared to the control group.