2172819-73-5
中文名稱
(S,R,S)-AHPC-CO-C3-酸
英文名稱
L-Prolinamide, N-(4-carboxy-1-oxobutyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
CAS
2172819-73-5
分子式
C27H36N4O6S
分子量
544.66
MOL 文件
2172819-73-5.mol
更新日期
2023/06/09 11:23:36
2172819-73-5 結(jié)構(gòu)式
基本信息
中文別名
(S,R,S)-AHPC-CO-C3-酸 英文別名
(S,R,S)-AHPC-CO-C3-acidVH 032 amide-alkylC3-acid
L-Prolinamide, N-(4-carboxy-1-oxobutyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
5-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid
物理化學(xué)性質(zhì)
沸點879.1±65.0 °C(Predicted)
密度1.288±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
酸度系數(shù)(pKa)4?+-.0.10(Predicted)
形態(tài)powder
應(yīng)用領(lǐng)域
用途一
VH 032 amide-alkylC3-acid is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC? research and development. It incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. VH 032 amide-alkylC3-acid is part of a range of functionalized tool molecules for PROTAC R&D.