2083630-26-4
2083630-26-4 結(jié)構(gòu)式
基本信息
中文別名
化合物 T28458 英文別名
PS-432PS432 >=98% (HPLC)
1H-Pyrrole-3-carboxylic acid, 2-[5-(4-chlorophenyl)-2-furanyl]-2,5-dihydro-4-hydroxy-1-(6-methyl-2-benzothiazolyl)-5-oxo-, ethyl ester
物理化學(xué)性質(zhì)
沸點662.5±65.0 °C(Predicted)
密度1.463±0.06 g/cm3(Predicted)
儲存條件2-8°C
溶解度DMSO: 2mg/mL, clear
酸度系數(shù)(pKa)4.50±1.00(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
PS432 is an allosteric inhibitor of atypical PKCs. It has been shown to target the PIF-pocket and significantly reduce tumor growth without side effects in mouse xenograft model.