206658-92-6
基本信息
鹽酸他克林水合物
他克林鹽酸鹽水合物
THA 鹽酸鹽 水合物
單滿吖啶氨 鹽酸鹽 水合物
9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE HYDRATE,99+%
安全數(shù)據(jù)
報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
2024/11/08 | S3639 | 9-氨基-1,2,3,4-四氫吖啶 鹽酸鹽 水合物 Tacrine hydrochloride hydrate | 206658-92-6 | 25mg | 1040.61元 |
2024/11/08 | S3639 | Tacrine hydrochloride hydrate | 206658-92-6 | 1g | 7944.3元 |
常見問題列表
Target | Value |
HNMT
() | |
cholinesterase
() |
Tacrine hydrochloride hydrate (12.5 to 37.5 nM) inhibits venom acetylcholinesterase as well as human serum butyrylcholinesterase in a concentration-dependent manner. The IC 50 is 31 nM for snake venom AChE and 25.6 nM for human BChE.
Pretreatment with Tacrine hydrochloride hydrate also modifies absolute levels of cocaine self-administration during reacquisition. Body weight declines approximately one-half percent over four days of treatment with intravenous Tacrine hydrochloride hydrate. Delivery of Tacrine hydrochloride hydrate by osmotic pump does not alter either linear- or repeated- cocaine-induced locomotor activity. There is no significant main effect or interaction with Tacrine hydrochloride hydrate treatment on active lever responding during reinstatement. Post hoc comparisons indicate that rats self-administering cocaine has significantly lower alkaline phosphatase levels, relative to Tacrine hydrochloride hydrate- but not saline- treated rats evaluated by conditioned-place preference.