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2053424-88-5

中文名稱 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
英文名稱 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
CAS 2053424-88-5
分子式 C21H29N6O5P
分子量 476.47
MOL 文件 2053424-88-5.mol
2053424-88-5 結(jié)構(gòu)式 2053424-88-5 結(jié)構(gòu)式

基本信息

中文別名
替諾福韋雜質(zhì)41
193-IM-C
替諾福韋拉酚氨酯雜質(zhì)7
替諾福韋拉酚氨酯雜質(zhì)08
替諾福韋艾拉酚胺雜質(zhì)08
替諾福韋艾拉酚胺酯雜質(zhì)7
替諾福韋艾拉酚胺非對映異構(gòu)體(RRR)
2-{(R)-[((R)-1-(6-氨基-9H-嘌呤-9-基)-1-甲基乙氧基]甲基}-苯氧基磷?;?BR>9-[(R)-2-[[(R)-[[(R)-1-(異丙氧基羰基)乙基]氨基]苯氧基氧膦基]甲氧基]丙基]腺嘌呤
TAF-IM-C(9-{(R)-2-[({[(R)-1-(異丙基氧基羰基)乙基]氨基}-苯氧基磷?;?甲氧基]丙基}腺嘌呤)
英文別名
Tenofovir Alafenamide Impurity 16
isopropyl(((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate fumarate
D-Alanine, N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester

物理化學(xué)性質(zhì)

熔點(diǎn)134 - 138°C
沸點(diǎn)640.4±65.0 °C(Predicted)
密度1.39±0.1 g/cm3(Predicted)
儲存條件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度可溶于氯仿(輕微)、甲醇(輕微、超聲處理)
酸度系數(shù)(pKa)4.21±0.10(Predicted)
形態(tài)固體
顏色白色至灰白色
穩(wěn)定性吸濕性
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