205187-53-7
205187-53-7 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)430.0±45.0 °C(Predicted)
密度1.549±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
常見(jiàn)問(wèn)題列表
生物活性
CX-157 是一個(gè)可逆的單胺氧化酶-A (MAO-A) 抑制劑，其 EC50 值為 19.3 ng/mL。靶點(diǎn)
EC50: 19.3 ng/mL (MAO-A)
體內(nèi)研究
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC 50 of 19.3?ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters.