2049025-45-6
中文名稱
OPC-345512
英文名稱
(R)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
CAS
2049025-45-6
分子式
C40H57N5O7
分子量
719.91
MOL 文件
2049025-45-6.mol
2049025-45-6 結(jié)構(gòu)式
基本信息
中文別名
卡非佐米雜質(zhì)16卡非佐米雜質(zhì) 11
英文別名
OPC-345512(αS)?-?α-?[[2-?(4-?Morpholinyl)?acetyl]?amino]?benzenebutanoyl-?D-?leucyl-?N-?[(1S)?-?3-?methyl-?1-?[[(2R)?-?2-?methyl-?2-?oxiranyl]?carbonyl]?butyl]?-L-?phenylalaninamide
(R)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
應(yīng)用領(lǐng)域
用途一
(αS)?-?α-?[[2-?(4-?Morpholinyl)?acetyl]?amino]?benzenebutanoyl-?D-?leucyl-?N-?[(1S)?-?3-?methyl-?1-?[[(2R)?-?2-?methyl-?2-?oxiranyl]?carbonyl]?butyl]?-L-?phenylalaninamide is an impurity of Carfilzomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.