196961-43-0
中文名稱
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
英文名稱
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
CAS
196961-43-0
分子式
C24H28O3
分子量
364.48
MOL 文件
196961-43-0.mol
196961-43-0 結(jié)構(gòu)式
基本信息
中文別名
化合物 T14912 英文別名
CD 32543-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
常見(jiàn)問(wèn)題列表
生物活性
CD3254 是一種有效的選擇性類視黃醇 X 受體 (RXR) 激動(dòng)劑。靶點(diǎn)
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RXR
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體外研究
CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L).
Cell Viability Assay
| Cell Line: | zebrafish ( Danio rerio ) embryos |
| Concentration: | 10, 20, 50, 100 μg/L |
| Incubation Time: | |
| Result: | The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day. |