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1610056-01-3

中文名稱 1610056-01-3
英文名稱 Peptide T TFA
CAS 1610056-01-3
分子式 C37H56F3N9O18
分子量 971.9
MOL 文件 1610056-01-3.mol
1610056-01-3 結(jié)構(gòu)式 1610056-01-3 結(jié)構(gòu)式

基本信息

英文別名
Peptide T TFA

物理化學(xué)性質(zhì)

儲存條件-20°C儲存
溶解度溶于二甲基亞砜
1610056-01-3價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2023/03/20HY-P0272A1610056-01-3
Peptide T TFA
1610056-01-31mg1000元
2023/03/20HY-P0272A1610056-01-3
Peptide T TFA
1610056-01-35mg2900元
2023/03/20HY-P0272A1610056-01-3
Peptide T TFA
1610056-01-310mg4900元

常見問題列表

生物活性
Peptide T (TFA) 是源自HIV-1 gp120的V2區(qū)的八肽。 Peptide T是 CD4 受體的配體,可阻止 HIV 與CD4受體結(jié)合。
靶點

CD4, HIV

體外研究

Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4. Peptide T at 10 -8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10 -9 M concentration significantly inhibits IFN-g production by PBMC.

體內(nèi)研究

Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE.

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