15727-65-8
中文名稱
1-乙炔萘
英文名稱
1-ETHYNYLNAPHTHALENE
CAS
15727-65-8
分子式
C12H8
分子量
152.19
MOL 文件
15727-65-8.mol
更新日期
2025/01/14 19:04:49
15727-65-8 結(jié)構(gòu)式
基本信息
中文別名
1-乙炔萘1-乙炔基萘
英文別名
1-naphthylethyne1-naphthylacetylene
α-ethynylnaphthalene
(1-Naphtyl)acetylene
naphthalene,1-ethynyl-
Naphthalene, 1-ethynyl-
1-Ethynylnaphthalene 97%
物理化學(xué)性質(zhì)
熔點(diǎn)1°C
沸點(diǎn)209.67°C (rough estimate)
密度1.070 g/mL at 25 °C (lit.)
折射率n20/D 1.6500(lit.)
閃點(diǎn)96 °F
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : ≥ 125 mg/mL (821.34 mM)
形態(tài)Liquid
顏色Colorless to light yellow
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H225
防范說(shuō)明P210-P403+P235
危險(xiǎn)類別碼10
安全說(shuō)明16
危險(xiǎn)品運(yùn)輸編號(hào)UN 1993 3/PG 3
WGK Germany3
常見問(wèn)題列表
生物活性
1-Ethynylnaphthalene 是細(xì)胞色素 P450 1B1 的選擇性抑制劑。靶點(diǎn)
P450 1B1
體外研究
1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E 2 ) by ~30% and 4-hydroxylation of E 2 by up to 80%.