153804-05-8
153804-05-8 結(jié)構(gòu)式
基本信息
中文別名
普拉沙坦 英文別名
FW 7203PRATOSARTAN
4(3H)-Cycloheptimidazolone, 5,6,7,8-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
物理化學(xué)性質(zhì)
沸點(diǎn)692.9±65.0 °C(Predicted)
密度1.32±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)4.15±0.10(Predicted)
常見問題列表
生物活性
Pratosartan 是一種選擇性的血管緊張素 II 受體拮抗劑。靶點(diǎn)
angiotensin II receptor
體外研究
Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT 1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders.