153758-25-9
中文名稱
4,5-Dihydroxy-6-((trifluoroacetyl)amino)-3-piperidinecarboxylic acid ( 3S-(3alpha,4alpha,5alpha,6beta))-
英文名稱
4,5-Dihydroxy-6-((trifluoroacetyl)amino)-3-piperidinecarboxylic acid ( 3S-(3alpha,4alpha,5alpha,6beta))-
CAS
153758-25-9
分子式
C8H11F3N2O5
分子量
272.18
MOL 文件
153758-25-9.mol
153758-25-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 T15470 英文別名
Heparastatin6-(trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid
3-Piperidinecarboxylic acid, 4,5-dihydroxy-6-[(2,2,2-trifluoroacetyl)amino]-, (3S,4S,5R,6R)-
4,5-Dihydroxy-6-((trifluoroacetyl)amino)-3-piperidinecarboxylic acid ( 3S-(3alpha,4alpha,5alpha,6beta))-
常見問題列表
生物活性
Heparastatin 是乙酰肝素酶 (heparanase) 的一個(gè)抑制劑。靶點(diǎn)
heparanase.
體外研究
Addition of 100 μM of Heparastatin (SF4) completely inhibits the enzyme activity of heparanase at a concentration of 0.15 μg/mL in an in vitro degradation assay. Addition of Heparastatin during the transition process does not affect the phenotypic change of TGF-β-treated cells.