144089-97-4
中文名稱
5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脫氧-2'-氟-N-(2-甲基-1-氧代丙基)鳥苷 3'-[2-氰基乙基 N,N-二異丙基氨基亞磷酸酯]
英文名稱
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS
144089-97-4
分子式
C44H53FN7O8P
分子量
857.91
MOL 文件
144089-97-4.mol
更新日期
2025/01/13 10:54:16
144089-97-4 結(jié)構(gòu)式
基本信息
中文別名
2'-F-DG(IBU) 亞磷酰胺單體N2-異丁?；?5'-O-DMT-2'-氟-脫氧鳥苷-3'-氰乙氧基亞磷酰胺
5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脫氧-2'-氟-N-(2-甲基-1-氧代丙基)鳥苷 3'-[2-氰基乙基 N,N-二異丙基氨基亞磷酸酯]
(2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-FLUORO-5-(2-ISOBUTYRAMIDO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE
英文別名
DMT-2FLUORO-DG(IB) AMIDITEibu-2'-F-dG Phosphoramidite
2'-F-dG(iBu)-CE Phosphoramidite
DMT-2'-F-dG(iBu)-CE Phosphoramidite
5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite
2'-fluoro-N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
所屬類別
有機原料：酰胺類化合物物理化學性質(zhì)
儲存條件-20°C
溶解度DMSO : 100 mg/mL (116.56 mM)
酸度系數(shù)(pKa)9.16±0.20(Predicted)
形態(tài)粉末
顏色白色至灰白色
InChIKeyCFFUQMXILRDKMM-QPYLYBSMNA-N
SMILESC(NC1=NC(=O)C2=C(N1)N([C@H]1[C@H](F)[C@H](OP(OCC)N(C(C)C)C(C#N)(C)C)[C@@H](COC(C3=CC=C(OC)C=C3)(C3=CC=C(OC)C=C3)C3=CC=CC=C3)O1)C=N2)(=O)C(C)C |&1:10,11,13,28,r|