141997-14-0
141997-14-0 結(jié)構(gòu)式
常見問(wèn)題列表
生物活性
sFTX-3.3 是一種 Ca2+ 通道拮抗劑，對(duì) P 型和 N 型 Ca2+ 通道的 IC50 分別約為 0.24 mM 和 0.70 mM。靶點(diǎn)
|
P-type calcium channel 0.24 mM (IC 50 ) |
N-Type Ca 2+ Channel 0.70 mM (IC 50 ) |
體外研究
sFTX-3.3 (100 μM) reduces the duration of the slow component of presynaptic calcium currents by about 50% of the control and also reduces presynaptic sodium current by approximately 20% of the control. sFTX-3.3 (100 μM) reduces whole-cell sodium current recorded from SK.N.SH cells by approximately 15%.