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1394820-77-9

中文名稱(chēng) 對(duì)甲苯磺酸寧格替尼
英文名稱(chēng) N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxaMide p-toluenesulfonate
CAS 1394820-77-9
分子式 C38H37FN4O8S
分子量 728.786
MOL 文件 1394820-77-9.mol
1394820-77-9 結(jié)構(gòu)式 1394820-77-9 結(jié)構(gòu)式

基本信息

中文別名
對(duì)甲苯磺酸寧格替尼
N-(3-氟-4-((7-(2-羥基-2-甲基丙氧基)喹啉-4-基)氧基)苯基)-1,5-二甲基-3-氧代-2-苯基-2,3-二氫-1H-吡唑-4-甲酰胺對(duì)甲苯磺酸鹽
英文別名
112176
CT-053
CT-053 tosylate
Ningetinib (Tosylate)
Ningetinib-Tosylate(tosylate)
Ningetinib Tosylate (CT-053 Tosylate)
N-(3-Fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-ph
N-(3-fluoro-4-((7-(2-hydroxy-2-Methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-diMethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxaMide p-toluenesulfonate
N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide 4-methylbenzenesulfonate
1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-, 4- methylbenzenesulfonate (1:1)

物理化學(xué)性質(zhì)

儲(chǔ)存條件Inert atmosphere,2-8°C
溶解度DMSO: 33.33 mg/mL (45.73 mM); Water: < 0.1 mg/mL (insoluble)
形態(tài)Solid
顏色White to off-white

應(yīng)用領(lǐng)域

用途1
一種TKI(小分子酪氨酸激酶)抑制劑。對(duì) c-Met、VEGFR-2和Axl的IC50值分別為6.7、1.9和<1.0nM。

安全數(shù)據(jù)

海關(guān)編碼2933998090
對(duì)甲苯磺酸寧格替尼價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱(chēng)CAS號(hào)包裝價(jià)格
2024/11/08HY-107145對(duì)甲苯磺酸寧格替尼
Ningetinib Tosylate
1394820-77-95 mg850元
2024/11/08HY-107145對(duì)甲苯磺酸寧格替尼
Ningetinib Tosylate
1394820-77-910mg1200元
2024/11/08HY-107145對(duì)甲苯磺酸寧格替尼
Ningetinib Tosylate
1394820-77-910mM * 1mLin DMSO1363元
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