1393112-45-2
中文名稱
拉帕替尼雜質(zhì)
英文名稱
Lapatinib 2-Fluoro Impurity
CAS
1393112-45-2
分子式
C29H26ClFN4O4S
分子量
581.06
MOL 文件
1393112-45-2.mol
1393112-45-2 結(jié)構(gòu)式
基本信息
中文別名
拉帕替尼雜質(zhì)47N-(3-氯-4-((2-氟芐氧基)苯基)-6-(5-(((2-(甲磺?；?乙基)胺)甲基)呋喃-2-基)喹唑啉-4-胺
N-(3-氯-4-((2-氟芐基)氧基)苯基)-6-(5-(((2-(甲基磺?；?乙基)氨基)甲基)呋喃-2-基)喹唑啉-4-胺
N-[3-氯-4-[(2-氟苯基)甲氧基]苯基]-6-[5-[[[2-(甲基磺?；?乙基]氨基]甲基]-2-呋喃基]-4-喹唑啉
N-(3-氯-4-((2-氟芐基)氧基)苯基)-6-(5-((((2-(甲基磺?；?乙基)氨基)甲基)呋喃-2-基)喹唑啉-4-胺 雙(4-甲基苯磺酸鹽)
英文別名
Lapatinib Impurity 45Lapatinib 2-Fluoro Analog
N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
N-[3-Chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine
N-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
應(yīng)用領(lǐng)域
用途一
3-Desfluoro 2-Fluoro Lapatinib is a compound related to drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.