1391712-60-9
中文名稱
CEP-37440
英文名稱
CEP-37440
CAS
1391712-60-9
分子式
C30H38ClN7O3
分子量
580.12
MOL 文件
1391712-60-9.mol
更新日期
2024/12/29 17:44:32
1391712-60-9 結構式
基本信息
中文別名
化合物CEP37440FAK和ALK雙重抑制劑(CEP-37440)
英文別名
CS-1603CEP-37440
CEP37440
CEP 37440
2-(5-chloro-2-{(S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino}pyrimidin-4-ylamino)-N-methylbenzamide
(S)-2-((5-chloro-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide
2-[[5-Chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide
Benzamide, 2-[[5-chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-N-methyl-
inhibit,Inhibitor,Cluster of differentiation 246,PTK2,triple-negative breast cancer,inflammatory breast cancer,CEP-37440,Anaplastic lymphoma kinase,FAK1,Anaplastic lymphoma kinase (ALK),Focal adhesion kinase,CEP 37440,PTK2 protein tyrosine kinase 2,autophosphorylation kinase,CD246,FAK,ALK tyrosine kinase receptor
所屬類別
生物化工：激動劑抑制劑物理化學性質
密度1.300±0.06 g/cm3(Predicted)
儲存條件2-8°C(protect from light)
溶解度DMF: 12 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
酸度系數(pKa)14.57±0.46(Predicted)
形態(tài)結晶固體
顏色Light yellow to yellow
