125720-21-0
中文名稱
FIBRONECTIN ADHESION-PROMOTING PEPTIDE
英文名稱
FIBRONECTIN ADHESION-PROMOTING PEPTIDE
CAS
125720-21-0
分子式
C47H74N16O10
分子量
1023.19
MOL 文件
125720-21-0.mol
更新日期
2024/11/03 16:22:43
125720-21-0 結(jié)構(gòu)式
基本信息
中文別名
纖連蛋白多肽FIBRONECTIN ADHESION-PROMOTING PEPTIDE 英文別名
WQPPRARIHEPARIN-BINDING PEPTIDE
TRP-GLN-PRO-PRO-ARG-ALA-ARG-ILE
H-TRP-GLN-PRO-PRO-ARG-ALA-ARG-ILE-OH
FIBRONECTIN ADHESION-PROMOTING PEPTIDE
Fibronectin Adhesion-promoting Peptide >=95% (HPLC)
Fibronectin Adhesion-Promoting Peptide / Heparin-Binding Peptide
L-Isoleucine, L-tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-
常見(jiàn)問(wèn)題列表
生物活性
Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) 是一種肝素結(jié)合氨基酸序列，這段序列存在于纖連蛋白 C-端的肝素結(jié)合域中。Fibronectin Adhesion-promoting Peptide 促進(jìn)間充質(zhì)干細(xì)胞 (MSC) 球狀體組裝成更大的聚集體。Fibronectin Adhesion-promoting Peptide 通過(guò)與細(xì)胞的肝素結(jié)合區(qū)反應(yīng)直接促進(jìn)內(nèi)皮細(xì)胞的粘附、擴(kuò)散和遷移。體外研究
GRGDS and Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide: WQPPRARI) micropatterns increase the endothelialisation of prosthetic materials in vitro. Fibronectin Adhesion-promoting Peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif.
RDGS and Fibronectin Adhesion-promoting Peptide promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts.