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1177279-49-0

中文名稱(chēng) NEBRACETAM HYDROCHLORIDE
英文名稱(chēng) 4-(aminomethyl)-1-benzylpyrrolidin-2-one hydrochloride
CAS 1177279-49-0
分子式 C12H17ClN2O
分子量 240.729
MOL 文件 1177279-49-0.mol
1177279-49-0 結(jié)構(gòu)式 1177279-49-0 結(jié)構(gòu)式

基本信息

中文別名
化合物NEBRACETAM HYDROCHLORIDE
英文別名
Nebracetam hydrochloride
WEB 1881 FU hydrochloride
4-(aminomethyl)-1-benzylpyrrolidin-2-one hydrochloride

物理化學(xué)性質(zhì)

儲(chǔ)存條件Store at -20°C, protect from light, sealed storage, away from moisture
溶解度溶于二甲基亞砜
形態(tài)Solid
顏色White to off-white

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H319-H335-H302-H315
NEBRACETAM HYDROCHLORIDE價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱(chēng)CAS號(hào)包裝價(jià)格
2024/11/08HY-113970ANEBRACETAM HYDROCHLORIDE
Nebracetam hydrochloride		1177279-49-05mg850元
2024/11/08HY-113970ANEBRACETAM HYDROCHLORIDE
Nebracetam hydrochloride		1177279-49-010mM * 1mLin DMSO935元
2024/11/08HY-113970ANEBRACETAM HYDROCHLORIDE
Nebracetam hydrochloride		1177279-49-010mg1350元

常見(jiàn)問(wèn)題列表

生物活性
Nebracetam hydrochloride 是 M1 毒蕈堿的激動(dòng)劑，會(huì)引起胞內(nèi) Ca2+ 濃度升高。其 EC50 值為1.59 mM。
體內(nèi)研究

Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms.

Animal Model: Male Wistar rats weighing 200-250 g.
Dosage: 10, 20 mg/kg.
Administration: P.O. (single dose).
Result: Able to correct this scopolamine-induced disruption of spatial cognition.
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