1159408-64-6
中文名稱
C79H128N10O36
英文名稱
4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl...
CAS
1159408-64-6
分子式
C79H128N10O36
分子量
1793.93
MOL 文件
1159408-64-6.mol
更新日期
2024/08/28 21:53:41
1159408-64-6 結(jié)構(gòu)式
基本信息
中文別名
6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(乙酰基氨基)-4,5-二乙酰氧基-6-(乙酰氧基甲基)(2H-3,4,5,6-四氫吡喃-2-基氧基)]戊?；被鵠丙基]氨基甲?；鵠乙氧基]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(乙?；被?-4,5-二乙酰氧基-6-(乙酰氧基甲基)(2H-3,4,5,6-四氫吡喃(2R,3R,4R,5R,6R)-3,4-雙(乙酰氧基)-6-{4-[(3-{3-[2-氨基-3-(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-雙(乙酰氧基)-6-[(乙酰氧基)甲基]-3-乙酰胺基四氫吡喃-2-基]氧基}戊酰胺基)丙基]氨基甲?；鶀乙氧基)-2-[(2-{[3-(5-{[(2R,3R,4R,5R,6R)-4,5-雙(乙酰氧基)-6-[(乙酰氧基)甲基]-3-乙酰胺基四氫吡喃-2-基]氧基}戊酰胺基)丙基]氨基甲?；鶀乙氧基)甲基]丙氧基]丙酰胺基}丙基)氨基甲?；鵠丁氧基}-5-乙酰胺基四氫吡喃-2-基]甲基乙酸酯
6-[4-[N-[3-[3-[3-[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(乙?；被?-4,5-二乙酰氧基-6-(乙酰氧基甲基)(2H-3,4,5,6-四氫吡喃-2-基氧基)]戊?；被鵠丙基]氨基甲?；鵠乙氧基]-2-[[2-[N-[3-[5-[(5R,2R,3R,4R,6R)-3-(乙?；被?-4,5-二乙酰氧基-6-(乙酰氧基甲基)(2H-3,4,5,6-四氫吡喃-2-基氧基)]戊?；被鵠丙基]氨基甲?；鵠乙氧基]甲基]-2-氨基丙氧基]丙?；被鵠丙基]氨基甲?；鵠丁氧基](3R,2R,4R,5R,6R)-5-(乙酰
英文別名
4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl... 所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
沸點(diǎn)1585.5±65.0 °C(Predicted)
密度1.31±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)13.13±0.70(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
VPN08646 is a triantenerrary N-acetylgalactosamine (tri-GalNAc) with an amino group, which is useful precursor for synthesis of GalNAc-LYTAC that engage the asialoglycoprotein receptor for targeted protein degradation. VPN08646 was first reported in Nat Chem Biol. 2021 Sep;17(9):937-946 (compound ). This product has no formal name at the moment.