115931-65-2
115931-65-2 結(jié)構(gòu)式
基本信息
中文別名
化合物 T14977 英文別名
CL 275838Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5-dihydro-4-[2-[4-(phenylmethyl)-1-piperazinyl]acetyl]-7-[3-(trifluoromethyl)phenyl]-
物理化學(xué)性質(zhì)
沸點(diǎn)636.7±55.0 °C(Predicted)
密度1.33±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)6.62±0.10(Predicted)
常見問題列表
生物活性
CL-275838 是一種記憶力提高劑，同時(shí)也是一種抗抑郁劑。體內(nèi)研究
CL 275,838 metabolism has sex-dependent differences in rat. CL 275,838 does not appreciably affect its own oxidation or cause significant hepatic microsomal enzyme induction in the male or female rat, except for slight enhancement of some components of the P450 system at doses (300?mg/kg once daily for 7 days) well above the effective pharmacological range.