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105882-69-7

中文名稱 偽赤蘚霉素A烯醇醚
CAS 105882-69-7
分子式 C37H65NO12
分子量 715.91
MOL 文件 105882-69-7.mol
105882-69-7 結(jié)構(gòu)式 105882-69-7 結(jié)構(gòu)式

基本信息

中文別名
紅霉素雜質(zhì)15
偽赤蘚霉素A烯醇醚
紅霉素雜質(zhì)F(EP)
假紅霉素 A 烯醇醚
偽紅霉素 A 烯醇醚
紅霉素雜質(zhì)F[表紅霉素 A 烯醇醚]
英文別名
LY 267108
NMIWBQUQCOMGHJ-XWVSLMRSSA-N
Erythromycin Ethyl succinate Impurity F
8,9-Anhydropseudo-erythroMycin A-6,9-heMiketal
Erythromycin Impurity 15(Erythromycin EP Impurity F)
Erythromycin Impurit F:(pseudoerythromycin A enol ether)
Erythromycin EP Impurity F/(2R,3R,6R,7S,8S,9R,10R)-3-((2R,3R)-2,3-dihydroxypentan-2-yl)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,6
(2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-Methylbutyl]-2,6,8,10,12-pentaMethyl-9-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one
4,13-Dioxabicyclo[8.2.1]tridec-12-en-5-one, 7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,6R,7S,8S,9R,10R)-
(2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one

物理化學(xué)性質(zhì)

熔點127.0-130.0 °C
沸點810.7±65.0 °C(Predicted)
密度1.20±0.1 g/cm3(Predicted)
儲存條件−20°C
酸度系數(shù)(pKa)13.45±0.70(Predicted)
形態(tài)neat

安全數(shù)據(jù)

WGK Germany3

常見問題列表

生物活性
Pseudoerythromycin A enol ether (LY267108) 是紅霉素的降解產(chǎn)物。Pseudoerythromycin A enol ether 無明顯抑菌活性。
體內(nèi)研究

Pseudoerythromycin A enol ether (LY267108) increases lower esophageal sphincter (LES) pressure in cats.

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