1030021-40-9
中文名稱(chēng)
CMP5
英文名稱(chēng)
CMP5
CAS
1030021-40-9
分子式
C21H22ClN3
分子量
351.88
MOL 文件
1030021-40-9.mol
更新日期
2024/12/03 21:43:11
1030021-40-9 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
CMP5 is a potent and selective PRMT5 Inhibitor. CMP5 showed to occupy hPRMT5 catalytic site and block symmetrically dimethylated S2Me-H4R3 & S2Me-H3R8 with no effect on the asymmetric methylation of H4R3 in lymphoblastoid cell lines at 40 μM. CMP-5 shows promise as a novel therapeutic_x000D_
approach for B-cell lymphomas.