Identification | Back Directory | [Name]
HUMAN NEUTROPHIL PEPTIDE-1 | [CAS]
99287-08-8 | [Synonyms]
HNP-1 HUMAN NP-1 HUMAN HNP-1 NP-1, HUMAN BD-1, HUMAN HNP-1 (HUMAN) HUMAN CRYPTDIN alpha Defensin-1 DEFENSIN-1, HUMAN α-Defensin-1, human neutrophil peptide-1 DEFENSIN HNP-1 (HUMAN) HUMAN ALPHA-DEFENSIN-1 RECOMBINANT HUMAN NP-1 ALPHA-DEFENSIN-1, HUMAN DEFENSIN-1, ALPHA-, HUMAN HUMAN NEUTROPHIL PEPTIDE-1 DEFENSIN HUMAN NEUTROPHIL PEPTIDE-1 HNP-1, Defensin Human Neutrophil Peptide-1 ACYCRIPACIAGERRYGTCIYQGRLWAFCC (DISULFIDE BRIDGE: 2-30,4-19,9-29) ALA-CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS H-ALA-CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS-OH H-ALA-CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS-OH (DISULFIDE BRIDGE: 2-30, 4-19, 9-29) ASP-HIS-TYR-ASN-CYS-VAL-SER-SER-GLY-GLY-GLN-CYS-LEU-TYR-SER-ALA-CYS-PRO-ILE-PHE-THR-LYS-ILE-GLN-GLY-THR-CYS-TYR-ARG-GLY-LYS-ALA-LYS-CYS-CYS-LYS (DISULFIDE BRIDGE: CYS5- CYS34, CYS12-CYS27, CYS17-CYS35) L-Cysteine, L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanylglycyl-L-α-glutamyl-L-arginyl-L-arginyl-L-tyrosylglycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalan... | [Molecular Formula]
C150H228N44O38S6 | [MDL Number]
MFCD00214572 | [MOL File]
99287-08-8.mol | [Molecular Weight]
3448.08 |
Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-20°C | [solubility ]
water: soluble1mg/mL, clear, colorless | [form ]
Solid |
Hazard Information | Back Directory | [General Description]
Chemical structure: peptide | [Biochem/physiol Actions]
Human neutrophil peptides (HNPs) is involved in endothelial cell dysfunction at the time of early atherosclerotic development.?HNP 1?3 can regulate the growth of atherosclerosis. HNP 1?3 levels are usually high in inflammation, including sepsis and acute coronary vascular disorders. |
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Sigma-Aldrich
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